What is the meaning of Acts 18:4-6?

4 And he reasoned in the synagogue every sabbath, and persuaded the Jews and the Greeks. 5 And when Silas and Timotheus were come from Macedonia, Paul was pressed in the spirit, and testified to the Jews that Jesus was Christ. 6 And when they opposed themselves, and blasphemed, he shook his raiment, and said unto them, Your blood be upon your own heads; I am clean: from henceforth I will go unto the Gentiles. (Acts 18:4-6 KJV)

William Burkitt’s Commentary

Observe here, How vehemently desirous the holy apostle was to plant a Christian church at Corinth, and to bring the Jews of Corinth to embrace the gospel: He was pressed in spirit, and testified, that is, reasoned with them with great vehemency and earnestness of affection, as well as with great judgment, concerning the Messias.

Observe, 2. That the Jewish synagogue at Corinth was the preaching place that St. Paul made choice of, hoping to gather the beginnings of his Christian church out of the converted Jews: He reasoned in the synagogue every sabbath day. Still, the apostle kept to his commission, to preach the gospel first to the Jews, and afterwards, upon their rejection, to the Gentiles.

Observe, 3. The blasphemous opposition which the Jews made to the doctrine of the gospel: They opposed themselves, and blasphemed; that is, they opposed his doctrine, reviled his person, and blasphemed Christ, whom that apostle preached.

Observe, 4. How the holy apostle clears himself of the blood of those Jews, whom he had now preached the gospel unto: He said, your blood be upon your own hands; I am clean.

The faithful ministers of Christ shall never have the blood of a perishing people laid to their charge; they having warned them of their damnable state, and discovered the way of life and salvation to them, deliver their own souls; whilst the people which they preached to, die in their sins, and for their sins.