What is the meaning of Matthew 25:42-45?

42 For I was an hungred, and ye gave me no meat: I was thirsty, and ye gave me no drink: 43 I was a stranger, and ye took me not in: naked, and ye clothed me not: sick, and in prison, and ye visited me not. 44 Then shall they also answer him, saying, Lord, when saw we thee an hungred, or athirst, or a stranger, or naked, or sick, or in prison, and did not minister unto thee? 45 Then shall he answer them, saying, Verily I say unto you, Inasmuch as ye did it not to one of the least of these, ye did it not to me. (Matthew 25:42-45 KJV)

William Burkitt’s Commentary

Observe here, 1. How Christ lays the charge of the wicked’s damnation upon themselves alone, Ye gave me no meat, ye took me not in: man, and man alone, is the cause of his own destruction and damnation.

Observe, 2. The kind of sin charged on the wicked at the great day.

Consider it, 1. In general, it is a sin of omission.

Whence learn, That sins of omission are certainly damning as well as sins of commission, or want of love to Christ and his members.

Learn thence, That one reigning sin, one prevailing corruption, is enough to damn a person, because it deprives a man of the grace of the gospel, and excludes him from all the benefit of the promises.

Note lastly, If such as do not give to Christ in his members shall be miserable at the great day, what will the condition of them be that take from them, who strip and starve them, who persecute and hate them, who imprison or banish them? If the uncharitable shall scarcely be saved, yea, shall certainly be damned, where shall the unmerciful and cruel appear?